By participating in the Encore-MDS study, you will be seen by experts who have experience treating MDS patients and receive an investigational drug.*

*RVT-2001 is an investigational drug which may or may not help your MDS. You also could experience side effects. If you move forward, your study doctor will discuss all potential benefits and risks with you.

Can I Participate?

You may be able to participate in the Encore-MDS study if you:
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Have a confirmed diagnosis of lower-risk* myelodysplastic syndrome.

*Lower-risk includes very low, low, and intermediate risk.

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Have required at least 2 red blood cell transfusions in the last 4 months.

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Have ring sideroblasts or a mutation in the gene called SF3B1.

Other eligibility criteria apply.

What You May Receive

By enrolling in this study, you will receive:

The study treatment/drug at no cost
Study related medical care for MDS
Travel reimbursement for research site visits

What Is The Purpose Of This Study?

The main purpose of this study is to determine the safety of the study drug, to find out what is the best dose for patients and to understand better how the study drug impacts anemia in lower risk MDS.

What's Involved

Step 1

Step 1


Click here to see if you may qualify for the study.
Step 2

Step 2

Phone Call

Upon initial eligibility, a PatientWing representative will call you and guide you through additional eligibility questions.
Step 3

Step 3

Informed Consent
If you qualify for the study, PatientWing will help connect you with a member of the study team at the study site. They will then discuss the details of study participation with you. The study doctor at a participating study center will go over the potential risk and potential benefits. If you decide to continue, you will be asked to provide your informed consent to participate in the study.
Step 4

Step 4

Official Screening
The team at a participating study center will determine if you are eligible to participate in the study.
Step 5

Step 5

If you meet the criteria to participate, during the study, you will take an oral study drug daily and have regular visits to the study clinic. More information will be provided to you during the informed consent process.
Caregiver helping patient

For Caregivers

The family, friends, and healthcare teams of those with MDS play an important role in supporting their loved one's health and wellbeing. If  you are a caregiver of someone with MDS, you can apply  for the study on their behalf by clicking  the button below.
You have the option to either enter the patient's information or your own contact information. Please speak with the patient prior to entering their information.


How do I get started?

Click See if you may qualify and enter your information to express interest in the study.

Why didn’t I qualify?

Research studies are designed in specific ways to test the study drug for safety and effectiveness. An answer you provided was outside the guidelines for this trial. This does not mean you will not qualify for different research studies.

Where is the study conducted?

This study is conducted at research sites throughout the United States, France, Spain, Belgium, Italy, South Korea and Taiwan.

How will the study drug be taken?

The study drug is taken as a pill by mouth every day. If you are enrolled into the study, your study doctor will tell you how much and how often to take the study medication.

What is the study drug being tested? How does it work?

The study drug being tested is RVT-2001, an investigational drug that has not been approved by the FDA or any regulatory agency yet. Because of improper mRNA splicing, people with lower-risk MDS are not able to produce red blood cells the way a healthy individual can.

Is there a chance I will receive a placebo?

No, everyone enrolled in this study will be given the study drug. There is no placebo.

Is there any cost for me to participate?

You will not have to pay for the study drug, study visits, or for the procedures needed for you to take part in this study. The study sponsor will pay for the costs of the study drug and any tests or procedures required for the study.

Will I receive compensation?

You may qualify to be paid back for reasonable travel expenses to and from the clinic for study visits.

Can I leave the study at any time?

Yes. Your participation in the study is completely voluntary and you may leave the study at any time.

Do I need health insurance?

If you do not have health insurance, it will still be possible for you to participate in this study.

About Study Team

About The Sponsor

Hemavant is a clinical-stage biopharmaceutical company dedicated to developing innovative targeted therapeutics to improve the lives of patients with blood disorders and hematological malignancies. To learn more, visit

About PatientWing

Our mission to bring better treatments to more people faster starts with you. We help sponsors find patients to participate in their clinical studies. With our focus on rare diseases and expertise in navigating the enrollment process, we're here for you every step of the way. To learn more, visit

Get in Touch With Us

Have a question? Call, email us or fill out the form. We're here to help.

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